... if at any time, the package drops below the dewpoint in your shop, water will condense...
OK, but how likely is that? In most cases it's all about the rate of temperature change inside the frame.
High humidity and air/surface temperature differential are both essential to the condensation of moisture, which occurs on surfaces considerably warmer than the air around them. Creating dew in a normal room may be possible, but that would be unusual -- and uncomfortable for occupants.
As air temperature in the room changes (cools), surface temperatures in the room would probably acclimate fast enough to avoid the dew point differential. The air temperature shift would have to happen very, very quickly. The larger the volume of air in the room, the more difficult it would be to create a dew point condition.
Just as a room is a closed-up environment, so is a picture frame. As in a room, humidity and air/surface temperature differential within the frame package are the factors that matter.
If the relative humidity inside the frame package were 50%, then a temperature differential of about 20 degF would be needed in order to condense moisture. Lower RH would require greater temperature differential; for example, if the RH were 30%, a temperature differential of about 35 degF would be needed.
A major benefit of a well-closed frame package is that is slows the rate of temperature change inside. In a frame with tight-fitting glazing, insulating filler boards and a tight, non-hygroscopic dustcover, the rate of change would be slowed and condensation inside would be less likely. A completely sealed frame would be even more effective in slowing the rate of change inside. An open frame, on the other hand, would be least effective in slowing the rate of change inside.
Now, if the frame were moved suddenly to a much cooler environment, condensation would be likely (warm gallery to car's cold trunk in winter). Condensation would also be more likely if interior temperature of the frame were suddenly warmer than room air (radiating sunlight through the glass).