As noted by others above, dew point is the issue here. If you look up a dew point chart online, you will see that moisture condenses on a surface under these conditions:
1. When humidity is present; more humidity = more condensation
2. When surface temperature is cooler than air temperature by a specific differential.
The dew point condition can develop quickly, and then go away quickly, as the temperatures of the air and the surface equalize and the differential diminishes. However, the resulting condensation may be visible for some time, as evaporation slowly takes place.
The air/surface temperature differential necessary to condense moisture varies according to temperature and humidity, which is clearly shown in a dew point chart. In typical ambient conditions of 70 F degrees and 50% RH, the air/surface temperature differential needs to be about 20 F degrees. But at 75% RH, the differential needs to be only 9 degrees, and at 85% RH, moisture condenses with a temperature differential of just 5 degrees.
Dew point condensation is the main reason why glass should never be placed in direct contact with items framed (abrasion is another reason). Glass is a poor insulator and transmits heat quickly, so when a frame is exposed to rapid, radical temperature change, dew point can occur easily. Acrylic is a better insulator and transmits heat more slowly, so the dew point usually will not occur. However, it still can occur if the change is rapid and radical enough.
There is no mystery to the dew point condition. To avoid the moisture in your frames, here are a few suggestions:
1. Avoid direct sunlight, because it radiates a lot of heat.
2. Keep your frames wrapped in insulating materials (blankets, paper, cardboard boxes, etc.) during transit and allow them to adapt to new ambient conditions slowly enough to avoid the temperature differential needed for the dew point.
3. Use acrylic instead of glass.
(Shameless plug: The DCO book includes a detailed description and illustrations explaining dew point, starting on page 41.)