48"x96"x 2 mm or 3 mm thick aluminum composite material (ACM) such as ePanel, DiBond, Alucobond, and other brands would make a good substrate. It is thin, lightweight, very rigid, non-hygroscopic, chemically inert and long-term stable. Among the best substrates for preservation framing, ACM is relatively inexpensive; about $35 to $65 per sheet, depending on the brand, size, and how and where you buy it. Most suppliers of this kind of material can cut it to size for you, using a Fletcher-Terry FSC wall-mounted cutter or a similar machine with a disk-type cutter that leaves smooth, rounded edges.
I would suggest lining the surface of the ACM with 4-ply alpha cellulose board and using sturdy pass-through hinges on the poster sections.
For the glazing, an optically coated, 98% UV filtering acrylic would be perfect. Or, if your customer will not pay that cost, use at least 98% UV-filtering acrylic. I'd use a spacer, too, but direct contact would be OK if the framed poster's surface would not be harmed by pressing the acrylic against it, and if it would be kept in a climate controlled environment.