I once had several Roman coins to mount and the woman wanted to be able to take them out and look at them after they were framed
What I did was bought some of the acrylic clay that hardens when heated in the oven. I used a color that looked like stone and shaped it into a square slab. Then I took each one of the coins and pressed them into the soft clay, making a perfect form to hold them.
The customer had given me some information about the coins which had some Roman markings discribing the coins. These markings were easy to duplicate, so I then scored them into the soft slab as well.
Now removing the coins first, I heated the slab in the oven to harden it. This slab had now become a perfect holder for the coins. I then cut a red suede mat board 5" and 5 1/2" larger than the slab itself , and then cut an opening in the suede mat board the same size as the slab to sink the slab into. Then from the back side of the mat, using silicone to edge around the slab, and 1/8" foam core to fill in around the part that was protruding through the back, I glued the slab to the foam core backing board.
Then using LJ's 403IG moulding and museum glass, I used the same red suede to shadowbox the frame. Since the Romans used a lot of red and ornate gold, this color combination looked very authentic when finished.
Remember, I said that the woman wanted to be able to take the coins out...so instead of sealing it up with a dust cover I used toggles on the back. Now she can drop the slab which is holding coins out at will. The coins rest in their places with no problem and she is able to hang the picture on the wall as well as show the coins to anyone who is interested. She is very happy with this piece and has been a great customer for over 9 years.