I would not want to put the spacer directly on the poster's edges. But on a few occasions I have used a very thin mat, about 1/2" to 1" wide, in a color that matches the poster's border, and a spacer under the glass that rests on the edges of the mat. The thin mat is not a visual feature, but it holds down the poster's edges, and also prevents the spacer from directly contacting the poster, where it could abrade, snag, or restrict movement within the frame.
In order to allow normal expansion and contraction without restricting movement of the frame's contents, be sure to install the fitting points loosely. If the frame rattles a little, that is a good sign. Moderately loose fitting is a good general rule for most* framing, but it may be especially important when the art's edges are so near the frame.
*As far as I know, tight fitting is a benefit only for framing that includes a direct contact overlay using acrylic, where the fitting process includes compressing the polyester batting to create spring tension in the assembly. Other than that, I try to fit the frame loosely enough that the contents can shift easily.