In an enclosure, comprising a window and back mat and a work on paper, that has been conditioned to 50% R.H. at 70 degrees, there are only a few drops of water and changes in temperature will not be able to cause condensation, in that package. Condensation accumulates on cool glass when sunlight passes through it and warms damp paper behind the glass, driving moisture out of the board. Mold will grow, when the R.H. is over 60% and that can easily occur in the summer months in houses in many costal regions. A modestly sealed frame can get slightly drier in the winter heating season and slightly damper in the summer, while it resiste extremes in the building. A completely sealed frame will resist change, as long is its seal holds.
Hugh